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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MFSD10
All Species:
7.58
Human Site:
S270
Identified Species:
12.82
UniProt:
Q14728
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14728
NP_001111.3
455
48339
S270
P
P
S
G
D
R
L
S
S
L
R
R
L
G
L
Chimpanzee
Pan troglodytes
XP_517077
405
43118
G238
R
A
P
S
M
A
L
G
F
R
D
A
A
D
L
Rhesus Macaque
Macaca mulatta
XP_001115142
512
54726
S270
P
P
T
G
D
R
L
S
S
L
R
R
L
G
L
Dog
Lupus familis
XP_545913
642
66749
A465
S
I
T
P
G
F
R
A
A
A
D
L
L
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2V8
456
49351
R271
P
P
A
E
H
R
L
R
N
L
R
R
L
G
L
Rat
Rattus norvegicus
B2RYH9
507
54917
T323
R
S
L
G
N
K
N
T
V
L
L
G
L
G
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506540
334
35116
L167
V
Y
F
L
Y
L
F
L
F
S
G
L
E
Y
T
Chicken
Gallus gallus
XP_420825
461
49829
Q279
A
P
S
D
Q
N
L
Q
N
L
K
I
L
G
L
Frog
Xenopus laevis
NP_001088384
454
49524
Q274
S
P
S
T
E
N
L
Q
K
L
R
L
L
G
M
Zebra Danio
Brachydanio rerio
NP_001017667
450
48935
Q269
P
P
S
E
Q
K
M
Q
N
L
K
V
L
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524429
477
51883
A300
N
V
P
K
K
D
I
A
A
L
R
S
I
G
L
Honey Bee
Apis mellifera
XP_625086
440
48862
T266
Q
D
K
K
N
L
K
T
L
G
Y
A
Y
F
I
Nematode Worm
Caenorhab. elegans
NP_510814
445
49487
V266
R
K
Q
E
M
Q
K
V
G
W
I
Y
F
L
F
Sea Urchin
Strong. purpuratus
XP_001181814
396
43728
L229
V
T
P
A
L
L
A
L
T
L
S
I
A
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87
77.5
55.6
N.A.
80
21.1
N.A.
42.8
64.2
63.2
58.2
N.A.
40
41
38.6
39.3
Protein Similarity:
100
87.9
80.4
58.7
N.A.
85.5
34.5
N.A.
54.2
76.7
77.1
72.9
N.A.
59.7
61.5
60.8
55.1
P-Site Identity:
100
13.3
93.3
6.6
N.A.
66.6
26.6
N.A.
0
46.6
46.6
46.6
N.A.
26.6
0
0
13.3
P-Site Similarity:
100
13.3
100
26.6
N.A.
80
46.6
N.A.
0
60
60
73.3
N.A.
53.3
20
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
8
0
8
8
15
15
8
0
15
15
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
8
15
8
0
0
0
0
15
0
0
15
0
% D
% Glu:
0
0
0
22
8
0
0
0
0
0
0
0
8
0
0
% E
% Phe:
0
0
8
0
0
8
8
0
15
0
0
0
8
8
15
% F
% Gly:
0
0
0
22
8
0
0
8
8
8
8
8
0
58
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
8
0
0
0
8
15
8
0
8
% I
% Lys:
0
8
8
15
8
15
15
0
8
0
15
0
0
0
0
% K
% Leu:
0
0
8
8
8
22
43
15
8
65
8
22
58
8
58
% L
% Met:
0
0
0
0
15
0
8
0
0
0
0
0
0
0
8
% M
% Asn:
8
0
0
0
15
15
8
0
22
0
0
0
0
0
0
% N
% Pro:
29
43
22
8
0
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
8
0
8
0
15
8
0
22
0
0
0
0
0
0
0
% Q
% Arg:
22
0
0
0
0
22
8
8
0
8
36
22
0
0
0
% R
% Ser:
15
8
29
8
0
0
0
15
15
8
8
8
0
8
0
% S
% Thr:
0
8
15
8
0
0
0
15
8
0
0
0
0
0
8
% T
% Val:
15
8
0
0
0
0
0
8
8
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
8
0
0
8
0
0
0
0
0
8
8
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _